University of British Columbia
Vancouver, British Columbia, Canada
An asymptotic reduction of the Gierer Meinhardt activator-inhibitor system in the limit of large inhibitor diffusivity leads to a singularly perturbed non-local reaction diffusion equation for the activator concentration. In the limit of small activator diffusivity, a one-spike solution to this non-local model is constructed. The spectrum of the eigenvalue problem associated with the linearization of the non-local model around such an isolated spike solution is studied in both a one-dimensional and a multi-dimensional context. It is shown that the principal eigenvalues in the spectrum are exponentially small in the limit of small activator diffusivity. The non-local term in the eigenvalue problem is essential for ensuring the existence of such exponentially small principal eigenvalues. These eigenvalues are responsible for the occurrence of an exponentially slow, or metastable, spike-layer motion for the time-dependent problem. Explicit metastable spike dynamics are derived by using a projection method, which enforces a limiting solvability condition on the solution to the linearized problem.